Melanie Esselen Selected Research

methyleugenol (methyl eugenol)

10/2017	Methyleugenol and selected oxidative metabolites affect DNA-Damage signalling pathways and induce apoptosis in human colon tumour HT29 cells.
11/2016	Methyleugenol and oxidative metabolites induce DNA damage and interact with human topoisomerases.
1/2013	Plant polyphenols and oxidative metabolites of the herbal alkenylbenzene methyleugenol suppress histone deacetylase activity in human colon carcinoma cells.

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Melanie Esselen Research Topics

Disease

12	Carcinoma (Carcinomatosis) 12/2021 - 05/2008
3	Poisoning 12/2021 - 03/2010
2	Neoplasms (Cancer) 04/2013 - 01/2013
1	Ergotism (St. Anthony's Fire) 10/2021
1	Cardiotoxicity 01/2021
1	Type 2 Diabetes Mellitus (MODY) 01/2019
1	Astrocytoma (Pilocytic Astrocytoma) 01/2018
1	Mycotoxicosis (Fungus Poisoning) 01/2018
1	Ataxia Telangiectasia (Louis Bar Syndrome) 10/2017
1	Carcinogenesis 04/2013
1	Colonic Neoplasms (Colon Cancer) 05/2011
1	Body Weight (Weight, Body) 03/2010

Drug/Important Bio-Agent (IBA)

8	DNA (Deoxyribonucleic Acid)IBA 11/2016 - 10/2008
4	PoisonsIBA 11/2016 - 03/2009
3	methyleugenol (methyl eugenol)IBA 10/2017 - 01/2013
3	Proteins (Proteins, Gene)FDA Link 10/2017 - 01/2013
3	ErbB Receptors (EGF Receptor)IBA 04/2013 - 05/2008
2	EnzymesIBA 12/2021 - 03/2010
2	methyleugenol-2',3'-epoxideIBA 10/2017 - 11/2016
2	3'-oxomethylisoeugenolIBA 10/2017 - 11/2016
2	Type I DNA Topoisomerases (Topoisomerase I)IBA 11/2016 - 07/2011
2	GlycosidesIBA 04/2013 - 05/2008
2	Doxorubicin (Adriamycin)FDA LinkGeneric 07/2011 - 03/2009
2	Anthocyanins (Anthocyanin)IBA 07/2011 - 05/2011
2	delphinidinIBA 10/2008 - 07/2008
1	FlavonoidsIBA 12/2021
1	nevadensinIBA 12/2021
1	AlkaloidsIBA 10/2021
1	asaroneIBA 01/2021
1	Glucose (Dextrose)FDA LinkGeneric 01/2019
1	enniatinsIBA 01/2018
1	Phosphotransferases (Kinase)IBA 10/2017
1	Checkpoint Kinase 1IBA 10/2017
1	A-Form DNA (A-DNA)IBA 10/2017
1	1'-(hydroxymethyl)eugenolIBA 10/2017
1	Silicon Dioxide (Silica)FDA LinkGeneric 05/2013
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2013
1	PolyphenolsIBA 01/2013
1	CamptothecinIBA 07/2011
1	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 07/2011
1	IceIBA 03/2010
1	Irinotecan (Camptosar)FDA LinkGeneric 03/2010
1	PlatinumIBA 04/2009
1	Type II DNA Topoisomerases (Topoisomerase II)IBA 03/2009
1	QuercetinIBA 07/2008
1	3-hydroxyflavoneIBA 07/2008
1	grandininIBA 05/2008
1	Ellagic AcidIBA 05/2008
1	vescalaginIBA 05/2008
1	Hydrolyzable TanninsIBA 05/2008

Therapy/Procedure

2	Chemoprevention 04/2013 - 01/2013
1	Therapeutics 01/2013